Find an article about plate tectonics(within the last 2 years Assignment

Discover an article about plate tectonics(within the most recent 2 years 2012-2014) and rundown the article - Assignment Example Behind this disclosure is Yin who was a notable UCLA teacher had practical experience in Earth space science and the creator who was answerable for the exploration. During the investigation that was done on the pictures caught by the NASA satellites utilizing its rocket called THEMIS (Time History of Events and Macroscale Interactions during Substorms) along with the HIRISE (High Resolution Imaging Science Experiment) ground-breaking cameras. The teacher took a sum of around 100 satellite pictures and broke down them which uncovered plate structural exercises, with his involvement with leading a great deal of land explore in territory like Himalayas and Tibet which hold world significant plates isolate, he took sharp investigation on the pictures from Mars and found that a ton of highlights seemed to be like those on earth particularly those that were discovered Himalayas, Tibet, California just as geomorphology. For example, the teacher found exceptionally smooth and simultaneously level gorge divider which can just create because of the impact of a shortcoming. There was additionally a lofty precipice that looked equivalent to that found around California’s Death Valley created because of the shortcoming. Yin additionally found straight volcanic zone which reach an inference of plate structural exercises. â€Å"These are highlights that are back to be found in our nearby planetary group separated from planet earth and Mars† said Yin, a teacher whose work is regarded by numerous and turn into the main story in August 9, 2012 issue of the basic diary lithosphere Mars surface has the absolute longest and most profound ever framework that contains ravines that has never been found in our close planetary system which is called Vallies Marineries. It is assessed to be around 2,500 miles long roughly multiple times more contrast with the earth’s Grand Canyon. Numerous researchers up to now are left thinking about how this was shaped, regardless of whether it was a major break that occurred on Mars’s shell driving it to open

Writing the Memo

Composing AN OFFICE MEMORANDUM If you fill in as a paralegal or law assistant after your first or second year of graduate school, you will doubtlessly invest a portion of your energy looking into and composing target memoranda, or official reminders. Normally, a lawyer requests that you give a reasonable investigation of the law as it applies to the realities of a client’s case. The intention is to advise †not convince. In spite of the fact that you ought to recall which end favors your customer, additionally remember that you will speak to the customer most successfully by being goal and realistic.The notice may be perused ordinarily †perhaps, over a time of months or years by a few unique lawyers, including the author, who may utilize it as an asset long after it is drafted. The lawyer will utilize the data contained in the notice to prompt the customer and may utilize it to set up a report that will at last be documented in court. For instance, an accomplice might be asking you whether a specific customer has a substantial lawful case. In the event that you reason that the appropriate response is â€Å"yes,†, at that point this will most likely transform into a claim. By then, a few pieces of the update might be consolidated when the objection is drafted.The notice may me counseled a third time when the lawyer reacts to a movement to excuse; a fourth time while drafting interrogatories; a fifth time before making a movement for synopsis judgment; a 6th time before preliminary; and a seventh during an intrigue, etc. Portions OF MEMO[1] 1. An update heading 2. The Issue (some of the time called Question Presented) states the question(s) that the notice settle. The Issue additionally separates the couple of realities that you foresee to be vital to the appropriate response. (For example, venture out costs to out-of-state, keeping youngster out of threat, and commission of crime).The peruser ought to comprehend the inquiry without alludin g to the realities. 3. Brief Answer (once in a while called Conclusion) expresses the writer’s forecast and sums up succinctly why it is probably going to occur. A few authors start with an immediate reaction, for example, â€Å"yes† or â€Å"probably not. † Our book says that they don't lean toward this. Now and again this is customer or accomplice driven. Additionally, a few inquiries loan themselves to answers, for example, â€Å"yes† or â€Å"no. † Allusion to determinative realities and rules. Try not to discard key realities. Start by just re-expressing your issue as a decisive sentence. Try not to discard the reasoning.Do exclude reference to power or use of important law. Numerous lawyers just read this part. 4. Realities set out the realities on which the expectation is based. 5. Conversation is the biggest and most complex piece of update. It demonstrates the end set out in a word answer. On the off chance that the conversation is excepti onally itemized or examines a few issues, it ought to be separated into subheadings. Here is what the notice will resemble and more data on each area. Notice TO:Senior Partner [Please square indent with the goal that the data lines up, as demonstrated] FROM:Your Name DATE:(date task is submitted)RE:(A succinct name for the issue considered: notice the gatherings; your firm will record your Memo by names and reason for actionâ€and, maybe, by purview) The best possible organization is in every case twofold dispersed. Try not to twofold space between segments. Plain old, normal twofold space is adequate. Realities Here, discuss every material certainty, as a rule in sequential request. A â€Å"material† actuality is a â€Å"dispositive† reality, or one whereupon the result will depend. Will influence the result somehow. It would be ideal if you incorporate all material procedural realities just as all material meaningful facts.This implies that it is basic to incorpora te every single applicable time, dates, and places. You should start with a â€Å"overview† sentence that sets the full setting and starts to portray the issue introduced. It would be ideal if you survey your perusing and however many examples as could reasonably be expected to comprehend both the range and extent of what is adequate as expert practice. Recollect your job Watch for the propensity to attempt to â€Å"prove† something by the manner in which you recount to the story. NO LEGAL ANALYSIS! 1) USE NEUTRAL LANGUAGE AND OBJECTIVE CHARACTERIZATIONS. As opposed to composing â€Å"the D was speeding through the school zone,† compose â€Å"the D was voyaging 50 MPH through the school zone. As opposed to composing â€Å"The D ruthlessly beat the victim,† compose â€Å"The D struck the P on the head, bringing about a cut over his left eye. † 2) Include ominous and ideal realities. QUESTION PRESENTED Phrased as an inquiry and consummation with a q uestion mark, express the particular issue or issues you will address. One strategy is to utilize the procedure: under? (portray the law); does? (express the issue); what? (give the lawfully important or â€Å"dispositive† realities). A few memoranda utilize the normally observed style of: â€Å"Whether . . . .† As usual, examine with your teacher to see which the individual in question prefers.But whatever the strategy, the accompanying counsel applies: †¢ Should be brief single sentences that incorporate important realities and general recommendations of law. †¢ Don’t state, â€Å"Whether a niece can recuperate for careless punishment of enthusiastic distress,† when you can say, â€Å"Whether, under Iowa law, a niece who observes the consequence of a car crash including her uncle from a street or two away can recoup for careless curse of passionate misery when she watches his serious wounds upon landing in the scene. † BRIEF ANSWER You stated (or asked) an inquiry in the segment above. Answer it here: â€Å"Yes. † â€Å"No. â€Å"Probably not. † Use a period. Your Brief Answer follows a similar equation and arrangement as your Question Presented. It responds to the inquiries â€Å"under? does? what? † aside from, the Brief Answer ought to incorporate a short proclamation of your reasons starting with the word â€Å"because. † DISCUSSION The core of a Memorandum, this segment requests that you clarify the law and clarify the realities. Getting it â€Å"right† will require some investment. Show restraint. You will probably â€Å"synthesize† the cases and concentrate a typical guideline of law. To do this, you should recognize the regular components that permit you to break down and examine a few cases at once.A basic misstep, legitimate journalists as often as possible participate in â€Å"listing conduct. † They treat each case autonomously and consecutively, starti ng each section with â€Å"In†Ã¢â‚¬for model, â€Å"In Callow v. Thomas† or â€Å"In Brown v. Earthy colored. † Looking down a composed page, the attorney will see a stepping stool like impact, the â€Å"in-ladder,† where each succeeding section starts with the word â€Å"in† followed by a case title. Regularly â€Å"listing behavior† comes full circle in â€Å"dump-trucking† when the legal advisor sets aside and â€Å"dumps† all the legitimate investigation into the last paragraph.In expansion, attorneys will every now and again â€Å"front-load,† crushing all the lawful guidelines of law into the absolute first passage. To maintain a strategic distance from these traps, start your conversation with a general review in a proposal or â€Å"roadmap† section. Your theory passage is the principal section in the Memorandum †and the main section in a Discussion segment. Continuously start your proposition section with a sentence to anticipateâ€and announceâ€your extreme end. Tell the peruser where you are going and be a visit manual for your contention or examination. At that point, taking each point in turn, compose a theory sentence that responds to the inquiries of â€Å"what-is-your-point? of this specific passage. Next, put forward the lawful Rule that applies. Incorporate the correct reference. Next, Analyze (clarify) what the law or lawful guideline implies. Next, Analyze (clarify) how the applicable realities fit (or don't fit) the lawful or authentic norm. At long last, Conclude each section with a summing up proclamation and each sub-issue with a particular sub-issue rundown. Some of the time, this technique is alluded to as a variety of the abbreviation: IRAC. Other lawful composing educators have some other abbreviation, for example, REAAC or FIRAC. In any case, others basically allude to it as the 5-advance procedure. Keep in ind that these are all â€Å"formulas† that lawful composing experts are utilizing to acquaint you with introducing a lawful contention. At last, you will utilize a style or equation that works best for your specific contention. In any case, for all intents and purposes each part of each legitimate contention must contain a 1) Statement of Rule or Applicable Law; 2) Analysis of the law and how it Applies to your significant realities; and 3) a Conclusion on every one of these sub-issues. So also, when a conversation requires a few passages, the essayist may not recreate the specific IRAC structure inside every single section, yet may require a few passages to grow completely the full set.As consistently, know your crowd and discussion about the technique for legitimate investigation that your educator, or later on, your manager, likes. What's more, recall that figuring out how to blend resolutions, cases, and auxiliary sources and afterward introducing them in a reasonable, brief, and intelligent way requires some seriou s energy and practice. A FEW IDEAS ABOUT WRITING †MEMORANDA[2] Many understudies, moving toward update composing just because, are frequently uncertain of how to continue. We have assembled a couple of tips for first (and second and third) time notice authors that we expectation will be helpful.Note: No single lot of rules might address all the issues identified with update composing. On the off chance that you have inquiries regarding a specific task, make certain to check with your teacher. 1. Discover the test(s). In allotting a notice, educators are for the most part assessing you on parsing a specific rule or test. At the end of the day, they need you to utilize different cases to clarify how your case either does or doesn't fulfill a test spread out for a situation or a resolution. For instance,

A Readers Guide to Lesser-Known LGBT Favorites

A Reader’s Guide to Lesser-Known LGBT Favorites Currently based out of Vancouver, British Columbia, Rachel  Rosenberg is a library technician and published writer; at 14, a short story of hers appeared in Chicken Soup for the Teenage Soul 2 and she can therefore be considered a literary equivalent to the little redheaded girl from 1982’s film adaptation of Annie. She has produced freelance articles, creative nonfiction essays and short stories. I’m very excited that Andrew Sean Greer’s Less recently won The Pulitzer Prize. The novel’s win surprised me because the book can basically be described as a queer romantic comedy, and Pulitzer winning books bring to mind books like Jeffrey Eugenides’s Middlesex or Toni Morrison’s Beloved. Large, physically heavy books about important social issues. I finished Less in two days and loved it enough to recommend to everyone I know via social media. It’s a fun, romantic, sometimes sad romp that takes our narrator, Arthur Less, across the world and back again. It brings up interesting points about writing, aging, and love. Maybe after you finish reading Less you’ll want some more wonderful LGBT reads? Here are some recommendations of books to help you feel the Arthur Lessâ€"shaped hole in your queer little heart. The Object of My Affection by Stephen McCauley Made into a cute movie staring Jennifer Aniston and Paul Rudd, the book is a total delight. The plot is that George and Nina are best buds living together when Nina suddenly gets pregnant. She breaks up with her overbearing boyfriend and asks George to raise the child with her; George, who is gay, assumed that he’d never have a child and is happy to take on this opportunity to find some more love. And then, complications ensue. A sweet, light novel with great characters that tells a warm and witty story about finding your own way to make a family. Stir Fry by Emma Donoghue Maria is 17 and has moved to Dublin for university. While looking for an apartment, she comes across an ad that states “2 ? seek flatmate. No bigots. Turns out the roommates are a lesbian couple, a fact that she realizes only after moving in with them. Ahh, youth. The story definitely falls under coming-of-age, as she struggles with to make sense of the lesbian relationship  (Dublin in the 90s was not a big place for diversity). It’s a well-written, cozy read. Girl Meets Boy by Ali Smith A modernized retelling of Ovid’s myth of Iphis: a woman disguises her daughter as a man, leading to the daughter eventually transforming into a man. Ali Smith sets her tale in Glasgow and London, as it alternates between sisters Imogen and Anthea. Anthea falls in love with a woman, while Imogen tries to understand her sister’s new relationship while also fighting her own battles with self-esteem. If you’ve read Smith before and found her too experimental, this is probably one of her more accessible reads but, make no mistake, her brilliant wordplay still fills the pages. The World Unseen by Shamim Sharif There was a movie of this one, too! A gorgeously written book about two Indian women living in South Africa; Marim is a stay-at-home mother, while Amina is a nonconformist who has started up a cafe with a black man, Jacob. The two women fall in love despite the fact that it is the 50s and Apartheid is still very much going on, and I appreciate the gradual way that their relationship blossoms. The stakes are high, which makes the romance even foxier, and I like that the novel shows how racism affects Jacob and other characters at well, foregoing focussing exclusively Amina and Marim. A really wonderful read that I won’t soon forgot.   Hello Darling, Are You Working? By Rupert Everett Did you know what actor Rupert Everett wrote novels? Well, if you don’t, I’m happy to tell you about this one. Everett brings us along on the madcap hijinks of a struggling ex-soap opera star named Rhys Waveral. Newly broke and between roles, Rhys realizes that he’s on the verge of being expelled from his hotel suite home and that he has to find a new way to make money. Enter: male hustling. The novel is fast-paced and glib, full of glamorous parties and reckless drug use. It was published in 1994 and I probably read it a few years after that, and the damn thing has stayed with me since. A weird, silly read. Sign up to Unusual Suspects to receive news and recommendations for mystery/thriller readers. Thank you for signing up! Keep an eye on your inbox.

Sickle-Cell Disease (SCD) or Sickle Cell Anemia - Free Essay Example

Sample details Pages: 8 Words: 2382 Downloads: 4 Date added: 2017/06/26 Category Medicine Essay Type Essay any type Level High school Did you like this example? Sickle-cell disease Sickle cell disease (SCD), or sickle cell anemia, is a group of genetic conditions, resulting from the inheritance of a mutated form of the gene coding for the ? globulin chain of the hemoglobin molecule, which causes malformation of red blood cells (RBCs) in their deoxygenated state. Specifically, this single point mutation occurs at position 6 of the ? globulin chain, where a valine is substituted for glutamic acid (Ballas et al. 2012). Don’t waste time! Our writers will create an original "Sickle-Cell Disease (SCD) or Sickle Cell Anemia" essay for you Create order This abnormal hemoglobin causes a characteristic change in the RBC morphology, where it becomes abnormally rigid and sickle-like, rather than the usual biconcave disc. These cells do not flow as freely throughout the circulatory system as the normal phenotype, and can become damaged and hemolysed, resulting in vascular occlusion (Stevens and Lowe 2002). SCD is an autosomal recessive condition, thus patients with SCD will have inherited a copy of the mutated gene from each of their parents (homozygous genotype). Individuals who only inherit one copy (heterozygous genotype) are termed sickle cell (SC) carriers, who may pass on the affected gene to their children (Stevens Lowe 2002). The severity of SCD varies considerably from patient to patient, most likely as the result of environment or other unknown genetic factors (Bean et al. 2013). Patients with SCD are typically of African or African-Caribbean origin, but all ethnic groups may be affected. In 2014 the National Inst itute of Clinical Excellence (NICE) estimated that between 12,500 and 15,000 people in the UK suffer from SCD (NICE quality standard 58, 2014), with more than 350 babies born with SCD between 2007 and 2008. Patients in developed countries typically live into their 40s and 50s. However in developing countries, it is estimated that between 50% (Odame 2014) and 90% of children die by the age of 5 (Gravitz and Pincock 2014). SCD is more prevalent in the ethnic African population because SCD carriers exhibit a 10-fold reduction in severe malarial infection, which is common in many African countries and associated with significant mortality. One proposed mechanism for this is that on infection with the malarial plasmid, RBCs in SCD carriers become sickle shaped and are then removed from the circulation and destroyed. Consequently, it is genetically beneficial to be a SCD carrier, thus more SCD carriers survive to reproduction age, in turn increasing the incidence of the SCD mutat ion in the population. (Kwiatkowski 2005). SC patients experience periods of acute illness termed â€Å"crises† resulting from the two different effects of SCD; vaso-occlusion (pain, stroke and acute chest syndrome) and those from hemolysis (for example, anemia from RBC destruction and inefficient oxygen carrying capacity) (Glassberg 2011). The frequency of these may be several times a week, or less than once a year. Patients typically present with anemia, low blood oxygen levels and pyrexia (NICE quality standard 58, 2014). There are 3 classifications of crises: 1. Sequestration crisis (rapid pooling of RBCs in organs, typically the spleen, which may result in patient death from the acute reduction in available red cells for oxygen transportation). 2. Infarctive crisis (blockage of capillaries causing an infarction). 3. Aplastic crises (where the spleen is damaged from 12 which compromises RBC production (Stevens Lowe 2002). The result of these cri ses can be irreversible damage to a wide range of organs from the spleen to the retina which can cause extreme pain (Stevens Lowe 2002). However, patients not currently experiencing a crisis can also present with anemia as the result of poor oxygen transport function, loss of RBCs due to sequestration in organs such as the spleen and reduced red cell production as the result of impaired spleen function (Ballas et al. 2012). Typically, patients will initially present with an enlarged spleen in early childhood (due to pooling of malformed RBCs), which then becomes hypertrophied, ultimately resulting in a state of almost complete loss of function (autosplenectomy). Several complications of SCD are recognised, including impaired neurocognitive function, which is most likely the result of anemia or silent cerebral infarcts (Ballas et al. 2012). In the UK, SCD is usually diagnosed antenatally or in the first few weeks of life. Prenatal screening is offered to parents who may be at risk of carrying the SCD causing gene. NICE recommend that screening is offered early in pregnancy for high risk groups (ideally before 10 weeks gestation) or via a family origin questionnaire in low risk groups. Full screening can then be offered if family history is suggested. In the case of a positive test, counselling should be offered immediately, and the parents offered the option of termination of pregnancy (NICE Clinical Guideline 62, 2014). However, if screening has not occurred, SCD is one of the diseases screened for by the newborn heel prick test in the first week of life (NICE quality standard 58, 2014). In older patients or those not in countries where screening is offered, patients present with anemia or acute crisis. Histological analysis of blood samples can also reveal sickle shaped RBCs and the characteristic abnormal hemoglobin can be identified by high performance liquid chromatography or electrophoresis (Glassberg 2011). There are three approaches to treatment of SCD. The first is to manage the condition prophylactically in the hope of reducing the incidence of complications and crises. The second is to effectively manage crises, both to reduce the risk of organ damage and life threatening events, as well as control the severe pain associated with a SCD crisis. The third approach is to target the cause of the condition itself. Penicillin (de Montalembert et al. 2011) and folic acid are usually offered to patients in order to prevent complications by bacterial disease and are associated with a significant increase in survival and quality of life (NICE quality standard 58, 2014). Children are also vaccinated against pneumococcal infection. Transcranial doppler imaging of the cerebral vessels can be used to identify children at risk of stroke (de Montalembert et al. 2011). As previously discussed, SCD carriers are conferred some protection from malarial infection. Paradoxically, SCD sufferers display an increased sensit ivity to malarial infection and should also be treated with anti-malarial prophylaxis where appropriate (Oniyangi and Omari 2006). Hydroxyurea has been used in the treatment of SCD, as it appears to increase the production of fetal hemoglobin (HbF), thus reducing the proportion of abnormal hemoglobin although the exact mechanism of this is unclear (Rang et al. 1999). Suggested mechanisms include induction of HbF by nitric oxide, or by ribonucleotide inhibition. Other suggested mechanisms include the increasing of RBC water content and reduced endothelial adhesion, which reduces the incidence of infarction (Charache et al. 1995). Blood transfusion is an important tool in treating SCD, especially in children. It almost immediately improves the capacity of the blood to transport oxygen, and in the longer term as the â€Å"healthy† donor RBCs are not as destroyed as quickly as the sickle shaped RBCs, repeated transfusion is associated with a reduction in erythropoiesi s (RBC production) in the SCD patient, thus reducing the proportion of sickle shaped RBCs in circulation, which in turn reduces the risk of a crisis or stroke. Exchange transfusion is also possible, whereby abnormal sickle RBCs are removed from the circulating volume prior to transfusion with donor blood. However there are drawbacks to transfusion, namely the inherent safety risks such as immunological sensitivity, contamination of blood products with infectious disease and a lack of available donated blood (Drasar et al. 2011). The severe pain of a crisis must be controlled, most often with opioid analgesics. These are effective analgesics which act by binding to  µ, ? and ? receptors. The common approach is intravenous infusion of morphine either by continuous drip or patient controlled analgesia (PCA) pump infusion. Non-opioid drug options, including paracetamol, tramadol and corticosteroids may also be considered, but these drugs have a limit to the analgesia they can produce, whereas opioid drugs are more often limited by their side effects, such as respiratory suppression, vomiting and itching (Ballas et al. 2012). Bone marrow transplant is currently the only curative therapy for SCD. However it is dependent on locating a suitable donor with a HLA tissue match, usually from a healthy sibling. It is associated with some risks and complications including grant rejection, but generally is associated with a very positive prognosis (Maheshwari et al. 2014). As SCD is an autosomal recessive disease with one well identified causative gene, gene therapy to replace one copy of the faulty gene with a normal copy is of great interest to researchers. However this is very much still in development in humans and a 2014 review of SCD clinical trials found no trials of gene therapy as yet (Olowoyeye and Okwundu 2014) In addition to the acute effects of SCD, patients are also at risk from a number of potentially fatal consequence of SCD such as acut e splenic sequestration. In this condition, which often occurs after an acute viral or bacterial infection (classically parvovirus B19), the malformed RBCs become trapped in the sinuses of the spleen causing rapid enlargement. Patients will present with often severe abdominal pain and enlargement, pallor and weakness and potentially tachycardia and tachypnea. Patients may also suffer from hypovolemic shock from the significant reduction of available hemoglobin (acute aplastic crisis). This is managed by emergency treatment of the hypovolemia and transfusion of packed RBCs. Because the rate of recurrence for splenic sequestration is high (approximately 50%), a splenectomy may be performed after the patient has recovered from the event (NICE quality standard 58, 2014). Acute chest syndrome is also a serious complication of SCD and may be fatal. It is characterised by the occlusion of the pulmonary blood vessels during an occlusive crisis. Patients typically present with chest pain, cough and low oxygen levels (Ballas et al. 2012). It is also associated with asthma, and it is recommended that asthma in patients with SCD be carefully monitored. Treatment of acute chest syndrome is usually by antibiotics, bronchodilators if indicated and transfusion or exchange transfusion also considered (de Montalembert et al. 2011). Another consequence of rapid turnover of the abnormally shaped RBCs is the increased production of bile, which may cause hepatobiliary disease, specifically gallstones and vascular conditions of the liver. Liver pathology can result from ischemia-reperfusion injury following a crisis, endothelial dysfunction and overloading with iron as the result of the liver sequestering iron from the destroyed RBCs (Ballas et al. 2012). SCD patients are also at significant risk of ischemic stroke, resulting from a cerebral infarctive crisis, with one study suggesting that 11% of patients will suffer a stroke by 20 years of age, and 24% by 45. Chi ldren who suffer stroke may also go on to develop moya-moya syndrome, which is associated with s significant decrease in cognitive function and increased risk of further stroke (Ballas et al. 2012). SCD is a complex condition and is associated with significant challenges in treatment as it requires the use of a multi-disciplinary team to cover the wide range of its affects and significant prophylactic treatments. As discussed, the effects of these potential complications can be life threatening and have life changing consequences. An additional difficulty is that while screening, prophylactic and curative treatments are available in the developed world, they are not in the developing world where rates of the disease are in fact highest. In sub-Saharan Africa mortality is estimated to be between 50% (Odame 2014) and 90% (Gravitz Pincock 2014) yet in developed counties life expectancy ranges from 40s to 50s (Gravitz Pincock 2014). Currently, laboratory diagnosis and scree ning is prohibitively expensive in developing countries thus there is a need for the development of low cost techniques. The Gavi Vaccine Alliance also endeavors to make prophylactic treatment more available, specifically the pneumococcal vaccine. Of the therapies discussed here, hydroxyurea is likely to be the most affordable and increasing the availability of this would be of significant benefit and clinical trials have commenced in Africa in 2014 (Odame 2014). References Ballas, S.K., Kesen, M.R., Goldberg, M.F., Lutty, G.A., Dampier, C., Osunkwo, I., Wang, W.C., Hoppe, C., Hagar, W., Darbari, D.S., Malik, P. 2012. Beyond the definitions of the phenotypic complications of sickle cell disease: an update on management. ScientificWorldJournal., 2012, 949535 available from: PM:22924029 Bean, C.J., Boulet, S.L., Yang, G., Payne, A.B., Ghaji, N., Pyle, M.E., Hooper, W.C., Bhatnagar, P., Keefer, J., Barron-Casella, E.A., Casella, J.F., Debaun, M.R. 2013. Acute chest syndrome is associated with single nucleotide polymorphism-defined beta globin cluster haplotype in children with sickle cell anaemia. Br.J.Haematol., 163, (2) 268-276 available from: PM:23952145 Charache, S., Terrin, M.L., Moore, R.D., Dover, G.J., Barton, F.B., Eckert, S.V., McMahon, R.P., Bonds, D.R. 1995. Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia. N.Engl.J.Med., 3 32, (20) 1317-1322 available from: PM:7715639 de Montalembert M., Ferster, A., Colombatti, R., Rees, D.C., Gulbis, B. 2011. ENERCA clinical recommendations for disease management and prevention of complications of sickle cell disease in children. Am.J.Hematol., 86, (1) 72-75 available from: PM:20981677 Drasar, E., Igbineweka, N., Vasavda, N., Free, M., Awogbade, M., Allman, M., Mijovic, A., Thein, S.L. 2011. Blood transfusion usage among adults with sickle cell disease a single institution experience over ten years. Br.J.Haematol., 152, (6) 766-770 available from: PM:21275951 Glassberg, J. 2011. Evidence-based management of sickle cell disease in the emergency department. Emerg.Med.Pract., 13, (8) 1-20 available from: PM:22164362 Gravitz, L. Pincock, S. 2014. Sickle-cell disease. Nature, 515, (7526) S1 available from: PM:25390134 Kwiatkowski, D.P. 2005. How malaria has affected the human genome and what human genetics can teach us about malaria. Am.J.Hum.Genet ., 77, (2) 171-192 available from: PM:16001361 Maheshwari, S., Kassim, A., Yeh, R.F., Domm, J., Calder, C., Evans, M., Manes, B., Bruce, K., Brown, V., Ho, R., Frangoul, H., Yang, E. 2014. Targeted Busulfan therapy with a steady-state concentration of 600-700 ng/mL in patients with sickle cell disease receiving HLA-identical sibling bone marrow transplant. Bone Marrow Transplant., 49, (3) 366-369 available from: PM:24317124 NICE Clinical Guideline 62 Antenatal Care. Guideline CG62, published March 2008, revised February 2014. https://www.nice.org.uk/guidance/cg62 NICE quality standard 58: Sickle cell acute painful episode, Guidelines CG143, publication date June 2012, reviewed May 2014. https://www.nice.org.uk/guidance/cg143 Odame, I. 2014. Perspective: we need a global solution. Nature, 515, (7526) S10 available from: PM:25390135 Olowoyeye, A. Okwundu, C.I. 2014. Gene therapy for sickle cell disease. Cochrane.Database.Syst.Rev., 10, CD007652 available from: PM :25300171 Oniyangi, O. Omari, A.A. 2006. Malaria chemoprophylaxis in sickle cell disease. Cochrane.Database.Syst.Rev. (4) CD003489 available from: PM:17054173 Rang, Dale, Ritter 1999. Pharmacology, 4th ed. Churchill Livingstone. Stevens Lowe 2002. Pathology, 2nd ed. London, Mosby.

Perceptions Of The British And Indian War - 860 Words

Perceptions of Britain Many events happened during the period of time between 1763-1775, that changed Americans mindset from then until now. Certain people and certain events during this time frame affected the nation of the United States enormously. This time period changed the United States for better and for worse. Certain people like Thomas Paine and Samuel Adams, tenaciously tried to change the course of history; haven wars, such as the French and Indian war altered the perception of the American people. These events and people were some of the many facilitated with the defiance against the British. This essay will show how these altercations turned the People of the newly formed Americas against the British. During the time of 1763-1775 one of the occurrences that happened to affect the colonist’s perception of the British was the French and Indian War. The amazing thing is that the war itself was not the main factor of the colonist’s trouble with the British, but the time after the war that was the cause of trouble. During the war the British fought with France around the Ohio valley for the control of land. The Ohio valley was very important to both of the empires, because of the value of the land and the strategic point it held in the years to come. Although both had their struggles especially with the Native Americans that called this place their home. Most of the Native Americans sided with either the British or the French, because they thought that if they hadShow MoreRelatedThe French And Indian War877 Words   |  4 Pageshistory; wars, such as the French and Indian war altered the perception of the American people. These events and people were some of the many tha t facilitated the colonists’ defiance against the British. Altercations they encountered turned the people of the newly formed Americas against the British aiding in their quest for independence. During the time of 1763-1775, one of the occurrences that happened to affect the colonists’ perception of the British was the French and Indian War. The war itselfRead MoreThe Causes And Effect Of The French And Indian War1146 Words   |  5 Pages 7 Years of War â€Å"French and Indian war† What were the causes and effect of the war? Ana Rodriguez 6th period 03/10/15 What were the causes and effect of the French and Indian war? â€Å"The last and most destructive of the four Anglo-French Colonial wars, was the French and Indian war.† Took place on 1754-1763, and together with its European counterpart, the seven years war. Start with England declaring war on France, and ending with the Treaty ofRead MoreThe Philosophy of the American Settlers Westward Expansion Leads to Expulsion of the Native Americans1197 Words   |  5 Pageswould remove Indians. Due to the long history various conflicts between Indians and Americans, the American settlers were apprehensive toward the Indians, leading to the perceived need of the removal of the Indians for their safety. Andrew Jackson’s negative attitude toward of the Indians also aroused public sentiment against them. Jackson’s position as a leader gave him more influence on the people, who knew of the battles he had won against the Indians during his time as an â€Å"Indian fighter.† Read MoreThe Causes of the American Revolution Essay1689 Words   |  7 Pagesindependent of the British Empire. In April of 1775, after many transgressions on both sides, the colonists decided that they no longer needed, or wanted the support, protection, and leadership of the country that founded them. There were many factors, both immediate, and longstanding that lead to the decision to fight for freedom from British rule. The American Revolution had some of its beginnings in the French and Indian war. For seven years, Britain battled the French and Indian nations in theRead MoreThe Era Of Optimism Based On The United States Essay1644 Words   |  7 Pagesbelieved today. Though World War 1 was impactful it didn’t alter people’s perception on the importance of science and technology in our society. This is shown in the technological outcomes that the war essentially produced. Like the use of machine guns, airplanes and other artillery’s. Also World War 1 greatly affected the political, spiritual and cultural development of the United States, India and Germany. The United States was impacted greatly because of the war. The United States at the timeRead MoreIndia Challenges Of India s Indian Movement Of Independence1477 Words   |  6 PagesKweller​ 2W 11 May 2015 Gandhi challenges British rule in India When one imagines of the early 1940s’ Indian movement of independence, one figure readily clicks into the mind; the popular Mahatma Gandhi, who was an immensely leader in India. He was nicknamed Mahatma by most of his countrymen, a name that meant â€Å"The Great Soul†. This leader led to a remarkable change of the world far much beyond his sacrificial and successful struggle that led to the end of the British imperial rule in his nation, IndiaRead MoreAmerica, A Narrative History Essay1425 Words   |  6 Pagespopulations. On article that exemplifies the cultural differences between the Native Americans and the Spanish Explorers is the third-person biographical narrative called â€Å"The Collision of Cultures.† The narrative gives the reader insight on what the indians and the explorers pre-judgement of one another, based off of what the parties believed with their religion and moral. This article’s reader would be someone that showcases an immense inter est in a population’s psychology and culture. As well as, interestRead MoreTaking a Look at the American Revolution832 Words   |  3 Pagesconstitutional rights. For a long time, the British had left the colony to run itself and given the freedom, the North American settlers turned to unique forms of government to match their developing new identity as Americans. They did this by establishing representative legislatures, observing the set rights and freedoms ad holding democratic meetings, all of which gave the settlers a sense of a new identity. When the British lost in the French and Indian war, they turned their attention to AmericaRead MoreLove Marriage vs Arranged Marriage!635 Words   |  3 Pageschanging the perception of the Indian mind. Love marriage is supposed to provide freedom and more independence as compared to arranged marriages where the girl/boy is chosen by the parents. The usual question of love marriage voters against arranged one is that how can anyone marry the person whom they don’t know? Amid popular love lore like Soni Mahiwal, India always had a long tradition of arranged marriages. With the advent of the British and the subsequent introduction of British education systemRead MoreImpact of the First World War in Africa: The Development of the Continent1289 Words   |  5 PagesThe First World War marked a crucial moment in the history of the world through its developments and its consequences. It was not only the first conflagration that affected the world at a global level but also it represented a series of events that influenced countries and territories that were initially outside the immediate source of war. One of these regions was the African continent that was, until the end of the first world conflagration, a mix of colonies and territories belonging to European

Burning Bright Free Essays

Is It Love? â€Å"Burning Bright† is a story about an older woman marrying a man young enough to be her son. Marcie is almost sixty. When her husband Arthur died and the local help fell away, she endured incredible loneliness at the end of a five-mile dirt track until the church recommended a handyman, Carl, who could help out on the farm. We will write a custom essay sample on Burning Bright or any similar topic only for you Order Now This silent man from nowhere marries Marcie, but remains mysterious. In the twenty-first century, seeing an older women and a young man is common. For most people though, the question is if the couple is truly in love. Many older women and men have large sums of money which could be given to their younger spouse if they die. In Rosh Rash’s â€Å"Burning Bright,† Marcie is much older than Carl, and there is a huge disconnect in their relationship because of age. The first question that has to be answered is if Marcie’s marriage with Carl is a believable love story. I think that it is not really a true love story. There is a part in the story where Carl and Marcie are talking about why he has not been married, and Carl tells Marcie that she is not too old for him(Rash 7). Farther on in the story, when Marcie and Carl got together, they did not have the typical fairytale love story meeting. Carl met Marcie because of the preacher giving him some much needed work. He got laid off from his carpentry Job. Marcie dated Carl Just because she became lonely. Later, they are at dinner, and Marcie thought that their conversation would get more comfortable. When she tries to talk to him about the fire, Carl is very short with her on words and tries to make the conversation short. He did not like to be around her, so he would sit outside and attend to himself. When they go to bed, they show love to each other, but it is the same thing every day. It is basically a routine for them. One of the examples that they use for their routine would be when Marcie says, â€Å"But at night as she readied herself for bed, he’d always come in. Theyd lie down together and he’d turn to kiss her good night, always on the mouth. Three, four nights a week that kiss would linger and then quilts and sheets would be pulled back (Rash). † I found this particularly interesting at the end of the story when Marcie chooses to pray for rain. She is praying for Carl to stop burning items. She also praying for her quality of life back, something Carl could give her. Marcie mentions she thought the longer they were together, the more he would talk, but it is not so. I think that their marriage will probably not last as long as they want it too, but as long as their both trying to work things out together, as of getting Carl to talk they relationship should be great. Now days, couples Just like Marcie and Carl. Some relationships are different than Marcie and Carl’s relationship. What are some thoughts about the relationships in the world today that’s Just like Marcie and Carl? How to cite Burning Bright, Papers

The artfulness of courtship as displayed in three pieces of pre

The artfulness of courtship as displayed in three pieces of pre-twentieth century literature and Trainspotting Essay The definition of courtship is, to courtship with a view to marriage. Verb to court, attention paid to a person whose favourite love or interest is sought. Convention means how things are normally done. In my essay I am going to discuss and analyse three pieces of pre-twentieth literature and look at the way in which they portray the conventions and awareness of courtship. I will be discussing Pride and Prejudice by Jane Austin 1775-1817 which was published in 1813, two sonnets, one written by Drayton and the other Shakespeare. The third is from the novel Trainspotting written by Irvine Welsh The first example of courtship I am going to look at is the novel Pride and Prejudice, which is about a family The Bennets who have 5 daughters and wish for them to get married to rich wealthy men. In the 18th Century marriage was an institution for the rich. Poor people did not really marry as there was no social advantage, before common law relationships were usual amongst the lower classes. It was not until the 19th Century that marriage became a more widespread practice. We will write a custom essay on The artfulness of courtship as displayed in three pieces of pre-twentieth century literature and Trainspotting specifically for you for only $16.38 $13.9/page Order now However marriage had always been important for the wealthy because marriage was a contract between powerful families, and could ensure the future of their economic survival. Austens novels are a critique of the unequal role of women in society and also of the institution of marriage as a monetary contract. Love was not an important factor in wealthy marriages. If you courted someone it meant that you had serious intentions of marriage and there was a whole etiquette involved for example asking the father for permission to court his daughter. In Pride and Prejudice there are two proposals which take place, one between Elizabeth and Mr Collins, and another between Elizabeth once again and Mr Darcy. These both show ways in which they follow and break convention. First to take place is the courtship between Elizabeth and Mr Collins Mr Bennets cousin a clergyman who is expected from both his boss and social status, to have a dutiful wife. Mr Collins shows his awareness of courtship by trying to show that he knows all about the female response, and her reactions to the offer of marriage, That it is usual with young ladies to reject the addresses of the man whom they secretly mean to accept When Collins asked Elizabeth for her hand in marriage, she declines and Mr Collins was eager to court her, so he goes on about his reason for marriage hoping that she then would then accept his generous offer. He shows his acute awareness of convention when stating these reasons for marriage, I am to inherit this estate after death of your honoured father, who however, many live many years longer, I could not satisfy myself without resolving to chuse a wife among his daughters Mr Collins Follows convention when he seeks Mrs Bennets for her daughters hand whom Collins knew was eager to let one of her daughters marry him. He did this maybe because he knew Mr Bennet might have declined his request, but by doing this he does break convention. The second offer of marriage from Mr Darcy breaks convention in several ways. Darcy first breaks convention by not asking for permission from any of the parents, not even the mother. This is probably because he is very big headed and thinks he is too important to request permission from the lowly Mr Bennet. He also puts her down and makes her feel less important, His sense of her inferiority- of its being a degradation- of the family obstacles which judgement had always opposed to inclination were dwelt on with a warmth which seemed due to the consequence he was wounding, but was very unlikely to recommend his suit While they are very different, both proposals have something in common. Both Mr Darcy and Mr Collins expect Elizabeth to jump at the opportunity of marriage and accept although in both cases she declined. This is due to the fact that Elizabeth is one of the daughters that did not wish to marry for wealth and a certain future but for love. .u4c66361691bd3c3eaf17d052d99a4344 , .u4c66361691bd3c3eaf17d052d99a4344 .postImageUrl , .u4c66361691bd3c3eaf17d052d99a4344 .centered-text-area { min-height: 80px; position: relative; } .u4c66361691bd3c3eaf17d052d99a4344 , .u4c66361691bd3c3eaf17d052d99a4344:hover , .u4c66361691bd3c3eaf17d052d99a4344:visited , .u4c66361691bd3c3eaf17d052d99a4344:active { border:0!important; } .u4c66361691bd3c3eaf17d052d99a4344 .clearfix:after { content: ""; display: table; clear: both; } .u4c66361691bd3c3eaf17d052d99a4344 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .u4c66361691bd3c3eaf17d052d99a4344:active , .u4c66361691bd3c3eaf17d052d99a4344:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .u4c66361691bd3c3eaf17d052d99a4344 .centered-text-area { width: 100%; position: relative ; } .u4c66361691bd3c3eaf17d052d99a4344 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .u4c66361691bd3c3eaf17d052d99a4344 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .u4c66361691bd3c3eaf17d052d99a4344 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .u4c66361691bd3c3eaf17d052d99a4344:hover .ctaButton { background-color: #34495E!important; } .u4c66361691bd3c3eaf17d052d99a4344 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .u4c66361691bd3c3eaf17d052d99a4344 .u4c66361691bd3c3eaf17d052d99a4344-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .u4c66361691bd3c3eaf17d052d99a4344:after { content: ""; display: block; clear: both; } READ: Literary Analysis of Masque of the Red Death EssayHE is conventional in that he tells her his true feelings, My feelings will not be repressed. You must allow me to tell you how ardently I admire and love you The two Sonnets I will be comparing both are Shakespearean sonnets, and both follow the convention of the sonnet form; 14 lines, rhyming scheme ABABABCC, rhyming couplet, 10 syllables, grouped in sets of four, which are called quatrains. The traditional theme of the sonnet is love and romance. The convention of a sonnet form of poetry is traditionally used for courtship written by the man to the woman, usually only written by the upper class. The petrarchan sonnet uses elaborate similes and comparisons, usually to describe a lady as being more beautiful than nature, and uses a lot of hyperbole. The first sonnet I will look at is one written by Drayton, This sonnet is about his mistress and how she will spend no longer than the day with him, and sends him away at night. Drayton because of this blames night for his problems and expresses three arguments to his mistress. The first argument he addresses is that night is the time for love. He thinks this because when love is made it is usually done at night, Me thinks this time becommeth lovers best; Night was ordained together friends to keepe. Drayton then presents his second argument that it is conventional for everyone to spend time together at night, and that it is so natural even animals do so. The quiet evening yet together brings, and each returns unto his love at night Drayton uses dramatic hyperbole here, as this statement is not necessarily true. He only does so to try to convince his mistress that it is conventional, and that it is strange not to get together than actually being together. Drayton then presents his third argument, which is that he blames night for his troubles, for not being able to get together with his lady. O thou that art so curteous unto all, why shouldst thou, Night, abuse me only thus, that every creature to his kind doost call, and yet tis thou doost onely sever us? In this extract the night is being personified. Even though throughout the sonnet the man is complaining to both the nigh and his mistress, he still writes to show her how much he loves her and would like to be with her, day or night. Well could I wish it would be ever day, If when night comes, you bid me go away. He shows his love by saying in the extract above that even though you bid send me away at night, if I could then I might as well make it day all day, so I could still spend more time with my love. The second sonnet I will look at is one written by Shakespeare, it is conventional in the form of a sonnet although it mocks, parodies or inverts the traditional Petrerchan sonnet form. Shakespeare still chooses to compare his mistress to nature although he does not use hyperbole; in fact he chooses to insult the mistress using the comparison of nature. My mistress eyes are nothing like the sun, coral is far more red than her lips red. If snow be white, why then her breasts are dun; If hairs be wires, black wires grow on her head. Shakespeare fulfils the convention of the sonnet to the end of his sonnet in that he expresses his genuine love for his lady, mistress, and object of desire. He is more honest in the declaration of his love. I think my love is rare as any she belied with false compare He critiques those poets who use sickly sweet comparisons of love to all sorts of impossible things. .ua5d475b1819f455bd9fa73be8b050e36 , .ua5d475b1819f455bd9fa73be8b050e36 .postImageUrl , .ua5d475b1819f455bd9fa73be8b050e36 .centered-text-area { min-height: 80px; position: relative; } .ua5d475b1819f455bd9fa73be8b050e36 , .ua5d475b1819f455bd9fa73be8b050e36:hover , .ua5d475b1819f455bd9fa73be8b050e36:visited , .ua5d475b1819f455bd9fa73be8b050e36:active { border:0!important; } .ua5d475b1819f455bd9fa73be8b050e36 .clearfix:after { content: ""; display: table; clear: both; } .ua5d475b1819f455bd9fa73be8b050e36 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .ua5d475b1819f455bd9fa73be8b050e36:active , .ua5d475b1819f455bd9fa73be8b050e36:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .ua5d475b1819f455bd9fa73be8b050e36 .centered-text-area { width: 100%; position: relative ; } .ua5d475b1819f455bd9fa73be8b050e36 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .ua5d475b1819f455bd9fa73be8b050e36 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .ua5d475b1819f455bd9fa73be8b050e36 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .ua5d475b1819f455bd9fa73be8b050e36:hover .ctaButton { background-color: #34495E!important; } .ua5d475b1819f455bd9fa73be8b050e36 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .ua5d475b1819f455bd9fa73be8b050e36 .ua5d475b1819f455bd9fa73be8b050e36-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .ua5d475b1819f455bd9fa73be8b050e36:after { content: ""; display: block; clear: both; } READ: The Process of writing an EssayHe loves his mistress just the way she is, and doesnt compare her falsely to things in nature. The Third and final piece I will be looking at is Trainspotting. This scene takes place in an Edinburgh nightclub, where a guy called Renton comes off heroin and re- discovers his sex drive. In the nightclub he sees a young lady and it is love at first sight. This young lady is called Diane although Renton does not know how young Diane actually is. Renton follows several courtship conventions in this piece. He starts off by using an original/unique chat up line to engage Dianes interest by complimenting her on the way she handled the unwelcome advances of a man in the club, I was very impressed by the capable and stylish manner in which you dealt with that situation. I thought to myself: shes special Both Renton and Diane knowingly play with courtship convention, particularly the delivery and response to the chat up line. Do you find this approach normally works and dont us girls just love that. They both use this to their advantage to reach their goal, in this case getting together for sexual intercourse.

Math Homework Help For You Without Delay

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Biography of Thomas Cole, American Landscape Painter

Biography of Thomas Cole, American Landscape Painter Thomas Cole was the British-born artist who became known for his paintings of American landscapes. He is considered the founder of the Hudson River School of painting, and his influence on other 19th century American painters was profound. Cole’s paintings, and paintings by those he taught, are known to have influenced attitudes toward American expansionism during the 19th century. The glorification of the land and the panoramic views encouraged optimism toward settling the vast lands of the West. Cole, however, had a pessimistic streak which is sometimes indicated in his paintings. Fast Facts: Thomas Cole Known For: Founder of Hudson River School of painters, admired for his majestic landscapes of distinctly American sceneryMovement: Hudson River School (American romantic landscape painting)Born: Bolton-le-Moors, Lancaster, England, 1801Died: February 11, 1848 in Catskill, New YorkParents: Mary and James ColeSpouse: Maria Bartow Early Life and Career Thomas Cole was born in Bolton-le-Moors, Lancaster, England, in 1801. He studied engraving briefly in England before emigrating to America with his family in 1818. The family arrived in Philadelphia and resettled in Steubenville, Ohio, where Coles father established a wallpaper engraving business. After becoming frustrated working in the family business, Cole taught art in a school for a brief period. He also received some painting instruction from a traveling artist, and tried striking out on his own as an itinerant portrait painter. Portrait of Thomas Cole, American painter. Smithsonian Institution / Wikimedia Commons / Public Domain Cole realized he needed to be in a city with many potential patrons, and returned to Philadelphia, where he painted portraits and also found work decorating ceramics. He took classes at the Philadelphia Academy and, in 1824, had his first exhibition, which was held at the school. In 1825 Cole moved to New York City, where he began to focus on romantic landscapes, the beautifully lit panoramas that would become his enduring style. After taking a trip up the Hudson River, he painted three landscapes, which were displayed in the window of a Manhattan art store. One of the paintings was purchased by artist John Trumbull, who was widely known for his paintings of the American Revolution. Trumbull recommended that two of his artist friends, William Dunlap and Asher B. Durand, purchase the other two. Trumbull appreciated that Cole had been inspired by the wildness of American scenery, which other artists had seemed to ignore. On Trumbulls recommendation, Cole was welcomed into New York Citys cultural world, where he became acquainted with luminaries such as poet and editor William Cullen Bryant and author James Fenimore Cooper. Travels and Inspiration The success of Cole’s early landscapes established him so he could devote himself to painting full-time. He began to travel in the mountains of New York State and New England after purchasing a house in Catskill, New York. Photograph of Catskill Mountain House, a painting by American landscape artist Thomas Cole. Francis G. Mayer  / Getty Images In 1829 Cole sailed to England on a trip financed by a wealthy patron. He made what was known as the Grand Tour, visiting Paris, and then Italy. He stayed for weeks in Florence before going on to Rome, hiking much of the way. He eventually returned to New York City in 1832, having seen major works of art in Europe and having sketched scenery that would be used as material for landscapes. In 1836 Cole married Maria Barton, whose family lived in Catskill. He settled into a fairly comfortable life as a successful artist. The self-made gentry of the region admired his work and purchased his paintings. Major Works A patron commissioned Cole to paint five panels which would be known as The Course of Empires. The series of canvases essentially predicted what would become known as Manifest Destiny. The images depict an allegorical empire, and proceed from Savage State to Arcadian or Pastoral State. The empire reaches its zenith with the third painting, The Consummation of Empire, and then descends to the fourth painting, Destruction. The series ends with the fifth painting, titled Desolation. Thomas Coles The Course of Empire - Consummation, 1836, oil on canvas, 51 Ãâ€" 76 in, New York Historical Society.   Fine Art / Getty Images During the 1830s, as Cole was painting his Course of Empires series, he was harboring gravely pessimistic thoughts about America, lamenting in his journal that he feared the end of democracy. One of his major paintings, dating from 1836, is titled View from Mount Holyoke, Northampton, Massachusetts, after a Thunderstorm - The Oxbow. In the painting, a pastoral area is shown along with a portion of untamed wilderness. On close examination, the artist himself can be found in the middle foreground, on a promontory, painting the Oxbow, a bend in the river. In his own painting, Cole looks out over the tamed and orderly land, yet he is located in the wild land which is still darkened from the passing storm. He shows himself in communion with untamed American land, perhaps purposely keeping a distance from the land which has been transformed by human society. View from Mount Holyoke, Northampton, Massachusetts, After a Thunderstorm The Oxbow.   Getty Images Legacy Interpretations of Coles work have varied over time. On the surface, his works are generally appreciated for their majestic scenes and striking use of light. Yet there are often darker elements present, and many paintings have dark areas which seem to raise questions about the artists intent. Coles paintings show a profound reverence for nature, which can appear idyllic or wild and violent within the boundaries of the same canvas. While still a very active artist, Cole became ill with pleurisy. He died on February 11, 1848. His influence on other American painters was profound. Sources Thomas Cole. Encyclopedia of World Biography, 2nd ed., vol. 4, Gale, 2004, pp. 151-152. Gale Virtual Reference Library.Hudson River School of Painting. American Eras, vol. 5: The Reform Era and Eastern U. S. Development, 1815-1850, Gale, 1997, pp. 38-40. Gale Virtual Reference Library.The Hudson River School and Western Expansion. American Eras, vol. 6: Westward Expansion, 1800-1860, Gale, 1997, pp. 53-54. Gale Virtual Reference Library.

Tourist guide system Essay Example | Topics and Well Written Essays - 500 words

Tourist guide system - Essay Example base stations such as chain of cell base stations, units that are designed to be hand-held that are based on Off-the-Shelf Fujitsu Team Pad Units and visitor’s information as reflected in the PC back at the office. These stations are PC’s that are standard that have a link to the internet as well as a WaveLAN Card. Thus, these base stations enable broadcasting of data and information that is within the vicinity and transmissions of position information from the local cells. Additionally, a GPS can be fitted if more accurate information is needed. In order to be able to retrieve data from the device, one need to press the ‘info’ button which then displays all the information about the visitor’s current position. The version in this project is an advanced version of the former that displayed a number of position choices on the tourist’s location. This is because unlike the project guide device, the former version of the guide device did not have the search engine (Andrew, 2009). However, using the new version, the visitors’ position can be identified using a Guide Tag Insert Position. This label is useful in identifying a visitor’s location in a dynamic way. For example, a tourist can identify their location by just asking a question on his or her location. This approach has got many advantages over the earlier approach. Using this guide a visitor is able to make bookings online, able to identify his location, make text messages and also able to navigate to various places. The earlier a pproach did not have the ability to identify the location of the visitor and also was not portable like the latest model. According to Martin 1994, push based strategy of information delivery is found in the communication between the tourist and the guide. The delivery of information in this case can be non-interactive or can be interactive. For example if the delivery of information is done through a radio or television then interactions between the buyer and the

Global running and competitive status study of Shire plc 187 Essay

Global running and competitive status study of Shire plc 187 - Essay Example With around 15 brands operating under the umbrella of Shire Plc the company has not only enhanced their market place but also diversified their business operations (Shire, 2014). Recently Biopharmaceuticals Company AbbVie opted for taking over Shire Plc and after numerous reconsiderations and deals between both the organisations the deal was called off. The initial offer of AbbVie was  £27.3 billion which was then increased to $54.8 billion (Bennett and Chen, 2014). However, given the changes in the US Tax Inversion process, AbbVie backed out of the merger process for which they will have to pay a total of $1.6 billion to Shire Plc as breakup fee. Following this change in their strategic activities, Shire Plc experienced a steep fall of 27% in their share prices (Yahoo Finance, 2014). The target market of Shire Plc is patients suffering from behavioural health, gastrointestinal problems and other rare diseases (Shire, 2014). Shire Plc has also developed a good brand value in the market of regenerative medicines. The target markets selected by Shire Plc hold some of the largest consumer segments in the healthcare and pharmaceutical industry (Angell, 2004). One of the core competencies of the company is the diversity in their customer offerings. The interesting fact about the management process of Shire Plc is that all their business success has primarily come from their mergers, acquisitions and alliances (Market Line, 2014). The ability to integrate the various cultures with the organisational mission and vision has gained them a unique competitive advantage that provides both cost and differentiation advantages over their competitors. However, Shire Plc is still largely dependent on their Attention Deficit Hyperactivity Disorder (ADHD) drugs for generating market revenue while other categories such as medicines related to Gastrointestinal or Hereditary Angioedema are still not able to

Marketing and market entry strategy in india

Marketing and market entry strategy in india A market entry strategy maps out how to sell, deliver and distribute HMs products in another country such as India. When products and services are exported to another country, the strategy will define ways of obtaining contracts and delivering them in that country. If HM has decided to conquer the international market in India, it is opened to many choices. These options may include the cost, risk and the degree of control that the company will encounter in the country. In entering an international business, it is important that the management of the HM should be able to choose marketing entry strategies and carefully choose the product that the company will market in India. Exporting, is the simplest form of marketing entry strategy which includes direct or indirect method such as using an agent, in the case of direct method and counter trade if the company opted to implement an indirect method. Due to technological advances, direct marketing is staging a comeback, leading to a relationship orientation. Moreover, since HM wants to be known globally, there are many other ways the company can choose from like joint venture or export processing zone. The management of HM may decide to choose the export strategy and include in their operation the specific channels to market their product. Relationship marketing has revolutionized the traditional marketing and has become the biggest paradigmatic shift in marketing practice in recent decades.It has not only changed customers to advocate by replacing customer satisfaction by customer delight but has also increased quality service offers that exceeds expectations. Similarly, it will open new horizons for HM. It will trigger the HM to introduce new products and services. According to Berry and Parasuraman (1991: 25) relationship marketing concerns attracting, developing and retaining customer relationships. Relationship marketing will provide HM with necessary selling approach to cope with various challenges, set by the modern market in India. Relationship marketing transforms single usage to multiple service usage and will strengthen HM by providing them the wherewithal with which they can carry out effective customer services in India. Nowadays, competition in fashion industry and demands of customers are increasing constantly. They demand for global fashion company like HM where there are provisions for an incentive to the customer. So, strong commitment to customer care, attraction and maintenance at all levels are the top priority of HM, while dealing with the customers. Relationship marketing will help HM to overcome these problems and make the sales procedures much simpler. Palmer (2001) enumerated the components of relationship marketing as being: a focus on customer loyalty and retention; long term orientation; tracing identifiable buyers; distinguishing different levels of relationship between the buyer and the seller; high levels of customer dedication; and service quality as being the responsibility of every employee. Relationship marketing will transform indifferent customers into loyal clientele and emphasizes on their retention. Customer retention is the means to delivering long-term profitability in H M. Customer relationships management focuses on customer retention, and customer retention is believed to be more profitable than customer acquisition. Dawkins and Reichheld (1990) found that higher retention rate leads to higher net present value of customers. The longer customers can be retained by HM, the more and more tangible benefits will accrue from a sustained income stream. The end goal of relationship marketing is profit for HM. Saren and Tzokas (2000) raised the usefulness of relationship marketing in creating unique, difficult to imitate knowledge through the processes of interaction and dialogue with the customer. Knowledge about customers can only be enhanced if HM is able to maintain lasting relationships with their customers. The determinants of store choice, customer loyalty, patronage behaviour, customer retention and relationship marketing have been widely studied around the globe. Therefore, a considerable volume of literature exists, especially regarding fashion industry. However, there is still considerable scope for research in this field as the environment of fashion industry is in a constant state of flux and the emergence of new store formats in India has led to dramatic changes in consumer behaviour. New and existing fashion industry tend to provide a completely new experience for their consumers by offering sophisticated customer service, a wide and assorted variety of goods, breakfast ambience, quality imported and branded products. Since, fashion has invading people style of living and HMs the product that has been chosen to go international market. Hence, this research will suggest a marketing entry strategy for HM using Porters Five Forces model (Porter, 1980) and SWOT analysis of other HM companies in other countries. The company is a new entrant to the Indian Market, thus, this paper will provide a marketing entry strategy analysis for the company as it invade the market in India. Competitors Analysis Competitors analysis is very important since HM is a new entrant within the market place. It is essential so that the HM will be able to know their competitors and the possible strategy that they may use to level up such competitors and know the needs of the target market. Thus, this means that HM will enter the India as a beginning industry considering many competitors within the market place. Marketing Entry Analysis Utilizing Marketing Mix Marketing is considered as one of the most important element underpinning successful business creation and because of its complex applications, marketing is defined in a variety of ways (Sheth, Gardner, and Garrett 1988). According to Elliot (1990), the marketing concept was first promulgated in the late 1950s. The importance of marketing concept incorporates oft-repeated elements such as: customer orientation; integrated marketing efforts; and resultant profitability (Elliot, 1990). The marketing mix principles can be adjusted on a frequent basis to meet the changing needs of the target market and other dynamics of marketing environment (McCarthy, 2004). In relation to marketing plan, marketing mix includes both short term and long term strategies makes for a more profitable marketing mix. Long term strategies build brand/company awareness and give sales revenue a permanent, gradual boost. Short term strategies create a temporary, immediate revenue boost by giving buyers an incentive to purchase. By implementing both long and short term strategies, you can attend to immediate sales goals while building your business reputation and goodwill (Kyle, 2004). 1.1. Product HM AB (originally known as Hennes Mauritz) is a Swedish clothing company, known for retail of low-cost designer clothings. It was established in Và ¤sterà ¥s in Sweden in 1947 by Erling Persson, though at the time it only sold womens clothing and was called Hennes, which means hers in Swedish. Persson acquired the premises and inventory of a Stockholm hunting equipment store named Mauritz Widforss in 1968. Persson expanded into menswear and renamed the store to Hennes Mauritz, later abbreviated to HM (www.hm.com). H M is the worlds favourite and preferred designer of apparels and clothing for man and women. In addition, H M is also known not only for their fashion cosmetic but because of the quality of the clothes designed durability and the funkiness of its clothes. Through the online stores, HM provides the regional, continental and European Market an exclusive clothing designs. The main goal of HM is to provide innovative designs of apparels and clothes for different types of people in different countries all over the world. The company is known because of its strategy of providing clothing designs exclusively for each countrys preferences and needs. 1.2. Pricing H M is believed to have advantages when it comes to its pricing tactic. In order to be known into the market place and as a new entrant, the company will provide its target market with an affordable cost while providing them a high quality products and services. The company will be given the customer and client a price that is lesser than its competitors so that the consumer will be enhanced to buy and patronize the H M clothes and cosmetics. 1.3. Placement/Distribution The HMs products will be distributed directly to its clients and consumers in order to be known in the market place. HM products can utilize joint venture strategies with distinguished distributor of apparels, clothes and cosmetics, providing them with great offers, so as to market the product of the H M internationally. In 2003, HM announced its entry into the traditionally exclusive Milan fashion scene. It remains to be seen if HM and other low-end retailers will be able to find a market there. In February 2004, The Gap, another prominent international retailer, sold off all of its German outlets to its competitor, HM. HM launched its first American outlet on March 31, 2000 on New Yorks famous Fifth Avenue. Following the success its stores, additional outlets were opened in the SoHo, Gramercy, and Herald Square areas of Manhattan, followed by outlets in Upstate New York in Syracuse, Utica, and West Nyack. The brand then expanded to other regions of the country, including Chicago and its outlying suburbs. The first two HM stores to appear on the West Coast of the US opened in San Francisco, California on November 19th, 2005. HM opened its first Canadian store in Fairview Mall in Toronto and soon after, its store in Torontos Eaton Centre was opened in March 2004. Following great financial success, HM opened ten other stores within the Greater Toronto Area. Stores were also opened in Montreal in Spring 2006. HM continued its expansion in the Canadian market and doubled the number of stores in 2006. It planned new markets include Barrie, Hamilton, London, Kitchener/Cambridge/Waterloo, St. Catharines and Windsor and Ontario market, Fairview (Pointe Claire) shopping centre, Rockland Centre, the Galeries dAnjou and the Carrefour Laval. (www.hm.com) 1.4. Promotion/Communication HM can use video advertisements, print advertisements and the concept of e-marketing to promote its products. These promotion and communication strategy will tend to meet the consumers form different places everywhere, especially those target markets or the consumers in the working place. Moreover, since the trend in the market place today is the usage of e-marketing, the company will provide a website that any client can access. The use of the Internet is changing technologically advanced marketing overnight while different industries have been trying to use it as part of their marketing strategy. It does not only reconfigured the way different firms do business and the way the consumers buy goods and services but it also become instrumental in transforming the value chain from manufacturers to retailers to consumers, creating a new retail distribution channel (Donthu and Garcia, 1999). E-marketing is a powerful tool used that can be used by HM. E-marketing is defined as the process of achieving marketing objectives through the use of electronic communications technology (ICT). Smith and Chaffey (2001) have provided a 5Ss learning devices on how the internet can be applied by all business firms for different e-marketing tactics. These 5Ss are useful for HM and are se lling, serve, speak, save and sizzle. E-marketing or online marketing strategy can be used by HM to market its products. Thus, the HM has created its own website (www.hm.com). HM will use the e-marketing strategy is to keep in touch to different internet users and to be able to attract more clients and consumers. HM will use e-marketing to accelerate its business portfolio whether the user of the website is a customer, employee, stockholders, vendors, retailers or end customers. 1.5. Market Segmentation Marketing segmentation is defined as an aggregating process clustering people with similar needs into a market segment (Perreault McCarthy, 2002: 74). According to Ravesteyn (2005), customer segmentation is critical for an effective relationship marketing strategy. HM will provide its target consumers for its product by using market segmentation strategy. The segmentation of the market is a critical aspect of relationship marketing and the segmentation of business customers by HM must be in line with the different levels of relationship offered by the company. They need to make use of relationship marketing and management at segment or market level to identify the target market they intend pursuing (Stewart, 1995). Primarily, the context of the market segmentation for this company will be the Psychographics. Strydom, Cant Jooste (2000) identify the following four types of segmentation: demographic, geographic, psychographic and behavioural segmentation. Psychographics includes soc ial class, lifestyle, and personality variables (Chiagouris and Kahle, 2000). The end result of using these variables is a psychological profile of each market segment. Issues also examined the customers loyalties, habits and self-concept. Social class describes how individuals want their office automation will meet their comfort and satisfaction, what they consider important about their immediate surroundings, their opinions on various issues, and their interests. As lifestyle studies concentrates on what the consumer requires, using these study results as marketing strategies eventually became a marketing concept. The marketing concept is a basic philosophy that maintains that HM should endeavour to satisfy the needs and wants of customers through a coordinated set of activities that also allows the HM to achieve its goals at a profit. The HM must be able to consider its consumer, especially the demands of the consumer so as to let the business have an opportunity of having an expansion of its business portfolio as required by the consumers. The focus of this overview is on the behavioural segmentation process, which refers to the segmentation of buyers or customers into groups on the basis of their knowledge of, attitude towards, use of or response to a product or service of a HM. The behavioural variables identified by Kotler (2000) include: Occasions occasional buyers develop needs, purchase, or use products. Benefits refer to the benefits that buyers seek. User status includes potential users, regular users, non-users, first-time users or ex-users. Usage rate will include light, medium or heavy users. Loyalty status are classified as hard-core loyals, split loyals, shifting loyals and switchers. Buyers-readiness stages where the customers are either aware or unaware of the product or service, informed, interested, have a desire for the product or service and have intent to buy. Attitude enthusiastic, positive, indifferent, negative and hostile. Research Objectives: Relationship marketing will contribute significantly to the development of HM in India. Therefore, it becomes essential to study its applications in a fashion company in India. This study fulfils this need. The study addresses the different pros and cons of relationship marketing in a fashion company in India. Thus, the general purpose of this research investigation is to identify, describe and analyse factors that have an impact on relationship marketing, customer retention and customer acquisition in Indian fashion context. The main objectives of this study are given below, To identify, describe and analyse factors that will have an impact on relationship marketing, customer retention and customer acquisition in a fashion company and at HM in India. To appraise the views of customers of HM in India, how they feel about the companys relationship with them. To gain insight on how HM in India build customer relationship marketing tactics. To understand and determine the mediating role of customer behavior between relationship marketing and customer retention and acquisition. To indentify the market entry strategies for HM in India. Research Questions: What is the relationship marketing tactics practiced by the HM in India? What is the market entry strategy practiced by the HM in India? Deliverables: As it has been described in the objectives of the research project that the main purpose of this study is to examine the market entry strategies and relationship marketing by HM in India and customer relationships in Fashion Company and to find out how fashion company relationships with customers promotes its entry in India. The final product of this research project will be a report, containing the HMs relationship strategy and market entry strategy in India, what are their advantages and disadvantages. The report will contain the perceptions of employee and customers. Finally, the report will highlight some relationship marketing problems of HM and a fashion company and suggest some guidelines to remove these problems and improve its customers base in India. Research Methodology: Interested customer and would be customers of HM in India will be approached to collect the data. There are two kinds of data. Primary data Secondary data Primary data includes the information about relationship marketing and market entry strategy available from customers of HM in India. This also includes responses by the different employee of HM on the shop-floor. Secondary data will tell about the impact of relationship marketing in the retailers and the data has been available in their system. To collect the data, retailers employees, posted at different positions, will be contacted. Similarly, to assess the changes in retail services, caused by the relationship marketing, customers views will also be found out. The tools to collect this data will be the surveys. For this, employees and customers will be interviewed, where as to know the views of customers, different questionnaires will be prepared to ask them different questions. To analyze the collected data, different statistical techniques will be used. Qualitative research can be referred to as the opposite of quantitative research method. Any research method has its advantages and it disadvantages. Qualitative research is a study done that produces its results and findings that do not result from statistical means or other method of quantification. This method of inquiry requires a high level of intelligence and experience from the researcher to arrive at a more realistic and targeted data from the respondent. Quantitative research is referred to as a measurement of how people feel, think or act in a particular way and that this survey tend to include large samples from fifty to any number of interviews, structured questionnaires containing mostly closed questions that require questions along with set responds. This involves the clear statement of variables i.e. specifying the dependent and the independent variable. Resources: The most important thing to carry out any research project is to know the background, research objectives, and research methodology of the research project. For this literature is searched out. The University Library will be the primary source to review the literature. Books in hard and soft form will be obtained from the library. Similarly, different research journals and articles in the library will be valuable assets to prepare a comprehensive research report. To prepare the questionnaires, surveys done by Fashion Company to know the relationship marketing and market entry strategy will be used. Similarly new questionnaires, depending on the situation, will also be prepared. Project Plan: The project is divided into three stages. Literature review Interviews of employees of HM and their customers Report writing Literature Review: To carry out any research project, a research must be able to review the literature. This makes researcher aware of work, done by other people in the respective field. The main source of literature is the journals, in which different researchers publish their findings of problems. Interviews of retail employees and customers: In order to collect information on the impact of market entry strategy and know impact on relationship marketing in the Indian fashion company, the employees of HM will be interviewed. They will be asked about the positive and negative points of relationship marketing utilization in their stores. Similarly, customer views will be taken through the interviews. Considering all these views, suggestion to improve the customer services will be advised. Report writing: The final product of the research project will be a written report. The structure of my report will be divided in following categories, Introduction: In the introduction, the market entry strategy and history of relationship marketing use in fashion sector will be discussed and how different relationship marketing systems will be used to address the issues of HM, with the passage of time. Aims and objectives: In this part of report, purpose of the research project will be stated very clearly; what are the aims of the study and what are the problems, which will be discussed in the report. Research methodology: This is the core part of the report. After stating the problem, different research methodologies will be explained to gather the data. The primary source will be the interviews of the employees and customers. From these interviews, impact of relationship marketing and market entry strategy of HM will be assessed. The questions asked to employees and customers will be provided in the appendix of report. Conclusions: After describing the problems and research methods, suggestion will be advised to eliminate the highlighted problems. Risk: In order to carry out any research project, it is very important to study all the aspects of the project. One of the main aspects regarding any project is the risks involved. There are also some risks involved, regarding the research project under consideration. One risk can be privacy. HM employees can be duty-bound and show reluctance to give information about their working procedures and on relationship marketing operations, used in the fashion company. Impact and Beneficiaries of Research: The main objective of this research activity is to investigate the market entry strategies and relationship marketing by HM in India and customer relationships in Fashion Company and to find out how fashion company relationships with customers promotes its entry in India. This research can be very helpful for the fashion sector. For instance, it will analyze the effectiveness of relationship marketing and its market entry strategies in India. It will determine the views of HM employees about the introduction of relationship marketing in their working environment. From this, both positive and negative points about the role of relationship marketing in the fashion sector, put forward by the HM employees, can be known. Similarly, the customers views about the insertion of relationship marketing and the effect of HMs market entry strategy can be found out. Customers level of satisfaction about the HMs customer services can be assessed. This report will also show the comparison of differe nt strategies among different HMs companies worldwide and how they use relationship marketing to achieve the same target. By knowing the views of customers through this study, their difficulties while dealing with HM, can also be discovered. This report will also address these issues and suggest solutions to eradicate these problems. So, the major beneficiaries of this report are the management of HM and by considering the suggestions of the report, they can improve their market entry strategies, customer services and hence the customer relationship from HM will be invigorated.

50 Cent Curtis Jackson Critical Essay

Curtis James Jackson, known worldwide as 50 Cent, is one of the most successful rappers of his time. He has produced many hits as a singer, and one of his greatest hits is Many Men. The song was produced in 2003 in the album, Get Rich or Die Tryin. 50 Cent wrote Many Men after he was caught in a shooting where he was shot nine times from his hand, legs, and his chest. He miraculously survived the shooting. Once recovered from the shooting was when 50 Cent decided to write one of the greatest hits of all time that he has ever produced. The song shows a lot of emotion since it was about the shooting that almost took his life away. He talks about how a lot of people wish death against him when he’s trying to accomplish and succeed in life as a rapper. The reason why 50 Cent wrote this song was to express himself how he felt about the fact that people wanted him dead and actually tried to take his life away. The song starts off by saying, â€Å"Many men, wish death upon me blood in my eye dawg and I can’t see I’m trying to be what I’m destined to be And niggaz trying to take my life away† (Jackson). This quote explains the distress in 50 Cent’s voice by saying these lyrics. This quote means a lot, 50 Cent lets us know that many people wish he was dead, he also reflects to the night of the shooting with the blood in his eye, and how he’s trying to become a rapper and succeed and become famous while people are trying to take his life away. Those couple of lines shows a lot of where 50 Cent comes from. As a young boy he had a very hard lifestyle, dealing drugs and robberies were part of his daily routine as he would make a living. Working on music really helped straighten him up as he focused on becoming a name in the rap industry and getting away from the drug business. There were a lot of people that had hate on 50 Cent, which led to the shooting that night and which was meant to take his life away. The beat to the song goes really well to the flow of the lyrics, and makes the listeners really get zoned in to the song and to what message he’s trying to say in it. The chorus talks about people wishing death upon him and how he doesn’t cry anymore and doesn’t look up to the sky anymore, and for the lord to have mercy on him. He makes the readers feel the pain he went through and the pain he still goes through being 50 Cent. Being rich and famous like 50 Cent doesn’t mean you have everything made for you. Having a substantial amount of fame can sometimes lead to trouble, as we saw with the accident with 50 Cent. In the chorus it says, â€Å"Many men, many, many, many, many men Wish death ‘pon me Lord I don’t cry no more Don’t look to the sky no more Have mercy on me Have mercy on my soul Somewhere my heart turned cold† (Jackson). By 50 Cent saying this, you can easily comprehend the pain he was in and the damage that will always be there with him, both physically and mentally, for the rest of his life. The beginning of the song starts off with 50 Cent and a friend talking to each other. You can then hear a car racing towards them and braking really hard, and then you hear the shots being fired. He does this to reflect back to the shooting. By doing this he lets people know what this song was meant for and why he made it. Even though it was a horrific scene, he reflects on it to show people what he’s all about and how he came back from it. The lyrics for this song come from his bottom of his heart. He expresses himself in a very unique way, something not every rapper can do. The fact that he sings about his life gives the song more meaning to it, especially since it was about him in the brink of losing his life. One of the verses that stand out the most in the song says, â€Å"Are you illiterate nigga? You can’t read between the lines In the bible it says, ‘what goes around, comes around’ Almost shot me, three weeks later he got shot down Now it’s clear that I’m here, for a real reason ‘Cause he got hit like I got hit, but he ain’t fucking breathing† (Jackson). This verse really stands out in this song. He starts off by calling out the guy who shot him saying if he’s an â€Å"illiterate nigga†, and then referring to the bible in a very straight forward manner. He then refers to the guy shooting him and how three weeks later he got shot, so that’s how the bible line comes to play. He then says how the guy got shot just like he did but the shooter actually died unlike 50 Cent, that’s how he knows he’s meant to be in this world and things happen for a reason. By referring to the bible in that verse, it shows how 50 Cent is close to God and that he has a relationship with him. He uses another line in his song that refers to God and he says, â€Å"Every night I talk to god, but he don’t say nothing back I know he protecting me, but I still stay with my gat†. Once again this shows how he has a relationship with God. Mentioning God in a song must be really special for him. Even though he says how he knows he’s being protected by God, the line after that means that he still carries a gun with him. This shows how the incident really got to him to the point where he needs to carry a gun with him to feel safe even though he knows God is protecting him and by his side. Overall the song Many Men in the album Get Rich or Die Trying was an absolute success. 50 Cent expresses his feelings in a very unique way to the people about an incident that almost took his life away. As we may know now, 50 Cent is in this world for a reason. He would always be remembered as one of the greatest rappers of all time and for the name that he made for himself. Like he says in his song, â€Å"You can call me the Don†.